CiTIUS, a Singular Research Center on Information Technology (IT), looks forward to reach the highest impact not only from a scientific, but also from a technological and social point of view. As a whole, more than 100 scientists work currently at the center, including 30 senior researchers, 14 postdocs, and numerous predoctoral students. CiTIUS research strategy targets the excellence in the framework of 7 scientific programs: Machine learning; Advanced Computing; e-Health; Approximate Processing; Personal Robots; Autonomous Sensors and Natural Language Technologies. CiTIUS researchers publish more than 60 papers per year in indexed journals and congresses (SCI-Scopus) and defend around 10 doctoral theses per year. The center has also 15 software licenses and created two spin-offs: Situm Technologies and Imagames.